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The rabies vaccine is safe and effective.
The preventive vaccination does not offer complete protection but creates an immunological memory. This ensures that protective antibodies are quickly produced after revaccination.
After two doses the immunological memory is lifelong. In case of possible exposure to rabies, revaccination should be started as soon as possible, but the administration of antibodies (MARIG or HRIG) is never necessary, except in case of immunosuppression.
See also the general information about rabies.
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